Forbidden Medicine

Curled up barefoot in an overstuffed armchair, the woman delivers grapes to her mouth one-by-one to keep the post-chemo nausea at bay. Her right forearm is attached to a passageway of plastic tubing that climbs straight up over her shoulder to a standard IV drip unit. But these drips contain something much different from the toxic chemotherapy she’s been receiving. The serene woman, with her shock of just-barely-there gray hair, accepts this intravenous nourishment gladly because she believes it will help combat the mutation, the deviation, the thickening in her breast.

At first the misshapen cells were content simply to advance inside her—to multiply and establish a battleground. But soon they sought dominance. The situation turned dangerous, uncontrollable, like mob violence.

The cancer threatened to take her life.

Now the IV unit releases its “alternative” elixir of vitamins, supplements and natural substances into her body. Since many of the treatments offered here in Dr. Douglas Brodie’s office are illegal in California, the woman has had to travel from the Sacramento area to Reno, Nevada, for this therapy—what she calls her “boost.”

Once a lightning rod for controversy, Brodie was targeted in California during the 1970s by what was then called the Board of Medical Quality Assurance, for embracing a medical doctrine that emphasized “un-conventional cancer modalities.” The regulators put him on probation and attempted on multiple occasions to take away his medical license.

Today, Brodie has a thriving practice in Reno—the new destination of choice for many thousands of cancer patients, from Sacramento and around the world, who seek alternative and “holistic” therapies for cancer and other diseases.

Sitting in the armchair, taking her IV treatment along with the half-dozen other cancer patients who today occupy Brodie’s infusion room, the woman knows full well that Brodie “had his troubles” back in California. But she has no qualms about her decision to add his alternative therapy to her conventional medical regime for breast cancer. “Dr. Brodie helps build me up,” she says. “He helps my body be strong.”

It is no exaggeration to say that every American adult alive in 2002 knows someone who has been diagnosed, suffered and possibly died from cancer. Mother, sister, father, friend—it’s hard to understate just how deeply rooted this disease is in the hearts and minds of the ordinary individual. For this reason, many arrive at any discussion of a treatment with a personal history, with emotions flared and fear attendant.

A decision to follow conventional medical wisdom seems a logical and persuasive path. And when it comes to cancer, convention leads in just one direction, to the “big three” treatment modalities—surgery, radiation, chemotherapy. But even the most traditional medical experts admit that the “three,” though successful in forcing a steady percentage of remissions, are ultimately toxic strategies that have been something of a statistical failure. The mortality rate shows a slight decrease these last years, but the incidence of cancer (number of people diagnosed) continues to climb dramatically, according to the American Cancer Society. Almost 1.3 million new cancer cases are expected to be diagnosed this year; 600,000 Americans will likely die of the disease in 2002. Cancer accounts for at least 10 percent of the total cost of treating all health problems in the U.S. today. Even the standard-bearer journal of conventional doctoring, The New England Journal of Medicine, writes that despite more than $20 billion poured into cancer research, the ultimate result has been nothing less than a “qualified failure.”

For this reason, some cancer patients eschew traditional medicine entirely and turn completely to alternative therapies. A much larger percentage make a choice to combine the tactics of conventional and non-conventional medicine, to seek a mix that has become known as “complementary” cancer care.

But they’d better not look for the alternative option in California.

Somehow, the hotbed of health consciousness and New Age culture that is California has also become the least favorable state in the union when it comes to alternative treatments for cancer.

From his Reno office, safely across the state border from where he was almost shut down, Brodie laughs politely when asked what would happen if he tried to reconvene his practice in California today.

“I’d be in jail right now,” he says.

Like many physicians, Brodie has furnished his waiting room with comfortable couches, polite armchairs and piles of magazines. But a visitor here is likely to find copies of Vegetarian Times and Homeopathy Today on the side table instead of Fortune and Time. The controversial doctor, age 76, wearing Lands End loafers and a standard white coat, exudes the calm air of a man who learned long ago that speaking his mind might come at a price.

In a measured tone, Brodie describes his own conversion to alternative medicine. The seed, he said, was planted back in 1955 when after earning a medical degree from the University of Michigan and serving for three years in the military, Brodie began a term as chief medical resident at the Highland-Alameda County Hospital in Oakland. One of his duties was overseeing the cancer ward. “I watched them get sicker and sicker,” he says, describing the vomiting, nausea, malaise, anemia and hair loss. “It was my observation that, almost without exception, those cancer patients were in worse condition during and after their chemotherapy than they had been before.”

By the 1970s, Brodie had what he considers a turning point when doctors told a female patient with what appeared to be deadly bladder cancer that she only had a year to live and that she should have her bladder removed. The patient asked for Brodie’s opinion on whether to enroll in a hospital in Mexico that used laetrile (a controversial plant substance, found in the pits of apricots and other fruits, that some believe to have cancer-fighting qualities) and other forbidden substances. Brodie felt compelled to be honest with the dying woman. “I told her it seemed to me that whatever they did in Mexico couldn’t be any worse than what was happening to her in the U.S.”

The woman took the treatment in Mexico and underwent a miraculous recovery, says Brodie. He continued her care for many years afterward and was so impressed with her case that he began using some of these same methods on other patients. Over time, he began believing that what American medicine thinks about cancer “was wrong most of the time,” he says. “Cancer patients suffer from impaired immune systems,” he says. “In fact, some of us think that cancer occurs as a result of an impaired or deficient immune system.”

Brodie also developed a belief that certain entities benefited mightily from the strict allegiance to conventional therapies. He came to accept that the pharmaceutical industry was a lead player in what he calls “Cancer, Inc.”—a spider web of public-private-academic research laboratories, cancer nonprofits (such as the American Cancer Society), research bodies (such as the National Cancer Institute) and spin-off industries that benefited from an all-out allegiance to the big three—surgery, chemotherapy and radiation. “We’re talking about an established monopoly which, despite some progress, continues to vigorously oppose the development of alternative or natural methods of dealing with cancer.

“It’s a monopoly of thought as well as a monopoly of methodology.”

Dr. Sidney Scudder, chief of Clinical Affairs for Hematology and Oncology for UC Davis Medical Center, bristles when he hears such sentiments. “Many of the alternative providers believe the U.S. government isn’t doing all it can to fight cancer and that’s completely ridiculous,” he says. “They think conventional doctors don’t want to cure you. Give me a break!” A reputable local physician who has practiced conventional cancer care for 20 years, Scudder adds that treatments have improved significantly since the “bad old days” of cancer care 20 years ago. From his perspective, outcomes are “tremendously better than they used to be for cancer patients. The toxicity [with chemotherapy] is still there, but the tools we have to deal with it are much better.”

It was the mid-’70s when Brodie’s practice drew the attention of the Board of Medical Quality Assurance in California. “They came after me,” he says. He learned of the first BMQA charges by reading a local newspaper headline: “Warrant Issued for Doctor’s Arrest” under which it read “Physician Charged with 23 Felonies.” To Brodie’s horror, the article turned out to be about him. He had been issued no warrant, nor received notification on any pending arrest.

The felonies turned out to be 23 individual alleged “over-prescriptions” and the board later admitted in court that it had made an error in calling these felonies. The prescriptions themselves involved four patients, one of whom was a young man with Buerger’s disease, who had both legs amputated at the hip and both arms amputated at the forearm. “These were patients with chronic, intractable pain who, in my opinion, required narcotics,” said Brodie. But court documents allege that Brodie practiced a pattern of prescriptions with this man and the three other patients that constituted “clearly excessive prescribing of drugs.”

The trial, held before an administrative judge in Tahoe City, lasted several weeks. Brodie’s local patients and supporters crowded the courtroom. In fact, the group was boisterous in the doctor’s favor and was evicted from the trial for their vocal support. Eventually, Brodie was exonerated of wrongdoing.

Soon the BMQA came back a second time, charging him once again with over-prescribing. Once again Brodie was exonerated. Though court records make no mention of his controversial cancer therapy as an issue, Brodie feels certain he was being singled out for this reason. “It was widely known that these attacks on my license were because of my use of Laetrile and unorthodox approach to the treatment of cancer,” he says.

Frank Cuny, California legislative advocate for Citizens for Health, confirms that, in his experience, the charge of over-prescribing narcotics is a common method of attack when state regulators want to punish or “get rid” of a controversial doctor. “It’s difficult to discipline a doctor when it comes to alternative practices, so they hit them with something else,” said Cuny.

When the board charged Brodie for the third time, it was one time too many. The constant struggle had taken its toll. “I decided I just didn’t want to fight with them anymore,” says Brodie. In the late ’70s, he left his home in Tahoe City and moved 15 miles across the state line to Incline Village in Nevada. A decade later, he moved to Reno, continued his practice and, in 1997, wrote an independently published book, Cancer and Common Sense: Combining Science and Nature to Control Cancer, that depicts cancer as a battleground—not just inside human bodies but also when it comes to politics, profits and principle.

Interestingly, shortly after his move to Nevada, the state of California passed a new law making it a felony for a physician to offer any substance or procedure to a cancer patient other than chemotherapy, radiation and surgery.

Pete Riolo knows what it’s like to do battle. A former detective with the Sacramento Police Department, Riolo retired and went on disability at age 59 after taking a bullet to the back in the line of duty. Except for that injury, he’d hardly been sick a day in his life. “When I quit the department,” he says, still proud of his early stamina, “I had over 1,300 hours of sick leave built up.”

Sitting on a couch in his single-story suburban home in northeast Sacramento, Riolo, now 72, does not mince words about how he felt in February 1997 when he learned he had prostate cancer. “I was stunned,” he said simply. “I could hardly find my way out the door.”

A series of medical appointments at the powerful Sacramento HMO who insured him reinforced the original diagnosis. (Because of a later financial settlement regarding his medical treatment, Riolo will not disclose the identity of the HMO.) In fact, Riolo says the doctors told him his PSA (prostate-specific antigen) level was so high it wouldn’t do any good to operate. (When this type of cancer is caught early enough, doctors usually remove the prostate as a first strategy for cancer control, though this doesn’t always work and may cause impotence and incontinence.) One doctor told Riolo he had six years to live; another told him he had three. One administered a “hormone blocker” shot called Lupron, to keep the cancer at bay. A doctor Riolo later dubbed “Bela Lugosi” after the legendary horror film actor, told the ex-cop that if a Lupron shot didn’t stop the advance of the cancer, the hospital would have no choice, says Riolo, but to “cut off his testicles.”

All told, Riolo says he saw four different doctors about his cancer. They all repeated a terminal diagnosis. “They wanted to bury me,” Riolo says now with measured anger in his voice.

Not one to give up without a fight, Riolo began to do exactly what you might expect a former detective to do. He gathered evidence, sorted information, and interviewed people who had experience with cancer.

Riolo’s research led him to believe that the pharmaceutical industry had a powerful and vested interest in supporting only conventional modalities for cancer since they could never make money off natural substances that could not be patented. Indeed, the bible for those seeking well-researched information about complementary cancer care, Choices in Healing by Michael Lerner, agrees that the pharmaceutical industry is a very powerful force in American science, medicine, business and politics. “The industry must make large profits to realize a return on investment, particularly in a regulatory system where it costs $100 to $200 million to bring a new drug to market. In this environment, drugs that cannot be patented are of little financial interest to the industry.”

Ex-cop Riolo puts a more succinct spin on things: “I learned that making money, not finding cures, is what conventional medicine is interested in.”

In March 1997, Riolo’s search for help led him to Brodie who told him, simply, that he could help him control the cancer. Riolo’s PSA level had recently been charted at a frighteningly elevated level of 71.4. (Anything above 4.0 is a red flag for prostate cancer.) But Brodie told Riolo not to worry, he could help him get his PSA down. “Until Dr. Brodie, I felt like a man without a country,” says Riolo. For the first time, the stricken man felt there was hope.

In April 1997, Riolo and his wife traveled from Sacramento to Brodie’s Reno clinic for two weeks’ worth of daily IV infusion treatment sessions designed to strengthen his immune system. The infusions consisted of mega doses of vitamins A and C, thymus, digestive enzymes, shark cartilage, antioxidants, germanium and CoQ10, an immune-system enhancing enzyme, as well as other natural substances. According to Brodie, the selection of a particular intravenous mix for each patient is derived based on studies in the field of preventive medicine and his own years of practice with substances he says best enhance the immune system, especially in its battle against cancer.

For some patients, Brodie includes Laetrile in the IV drips. “I still find it useful,” he said of the controversial substance, sometimes called vitamin B-17. According to Brodie, the “cancer establishment” waged a successful PR war against Laetrile in the 1970s, and forced the medical community to fall in line with its perspective that the substance was dangerous. But Brodie vigorously defends his use of Laetrile. “It’s not a cure-all; it’s not a panacea,” he says. “But it helps. Very often we can get patients off narcotics or at least reduce the dosage of narcotics and they start to feel better, eat better, gain weight … sometimes we get lucky and the tumors regress.”

However, Scudder of UCDMC remains convinced, like most conventional doctors, that Laetrile is not an effective cancer treatment. “In the U.S. clinical trials showed Laetrile didn’t do anything for cancer,” he said. Even alternative health guru Dr. Andrew Weil, on his Web site, agrees that Laetrile has never been proved effective and is “a worthless cancer treatment.” Brodie shrugs when he hears such assertions. “These methods give us consistent positive outcomes,” he says. “I have no doubt, after years of personal observation, that the modern-era Laetrile protocols exert a direct, anti-cancer benefit.”

Riolo’s PSA continued to decrease. When he went home, Brodie put him on a diet program that favored fresh fruits and vegetables as well as whole grains and beans. He advised Riolo to avoid foods like red meat that were high in fats, and refined sugars as they, according to Brodie, would “rapidly feed the fire of cancer.” The importance of phytochemicals was emphasized—these are plant extracts one can find in cruciferous vegetables like broccoli, cabbage, cauliflower and Brussels sprouts. Riolo, who spent more than $7,000 on Brodie’s intravenous and oral treatments in 1997, began to apply the diet, took the recommended oral vitamins and supplements and began a regular course of physical exercise throughout the spring and summer. His PSA level continued to decrease. Brodie feels this outcome was due to the alternative treatments and Riolo’s choice to strengthen his immune system so it could better fight the cancer.

Soon Riolo told Brodie he was thinking of going even further in his search for healing. He’d investigated a program at the Hospital Santa Monica, just south of Tijuana in Mexico, and wanted to undergo their three-week cancer care treatment. Brodie told Riolo he had “no qualms” with that.

To many, such a hospital represents the quintessence of quack. The well-publicized 1980 death of Steve McQueen, age 50, at an “alternative” cancer hospital in Mexico represents a solitary—and very negative—association with such hospitals. However, others believe such places, all of which operate outside the FDA approved guidelines on safe medical practices, are sanctuaries for doctors who aid healing and may even “cure” cancer.

Among other things, the Hospital Santa Monica utilizes hydrazine sulfate and hydrogen peroxide treatments, both viewed to have no value as a treatment for cancer by the American Cancer Society. According to Scudder, the kind of alternative care practiced in such places constitutes non-care. “It’s totally unproven,” he says. “It’s a dangerous and slippery slope out there when it comes to alternative care. Much of it is about making money, not helping people. If there really were miraculous cures out there, they’d be on the market.”

Riolo spent $17,000 out of his own pocket for a three-week stay at the hospital in Mexico. Among other alternative treatments, he underwent the above-mentioned hydrogen peroxide therapy, including taking “oxygen baths,” based on the conviction—un-proven by scientific standards—that cancer cells cannot live in an oxygenated state.

Riolo has only positive things to say about his stay in Mexico. “I was seeing cancer cured there right before my very eyes,” says the ex-cop, who describes witnessing the progress of dozens of patients who, he says, underwent rapid cancer remissions. However, as conventional doctors would advise, cancer is known to go into spontaneous and rapid remission, regardless of treatment.

When Riolo got home, his PSA had dropped to 7.0, a reading that still indicated prostate cancer but showed a dramatic reversal. He continued on a home treatment plan that integrated Brodie’s vitamins, natural supplements and PC-SPES (a combination of mostly Chinese herbs that was recently outlawed as dangerous by the FDA) as well as other products only available in Mexico. At one point he was spending close to $1,000 per month on his home-care treatments. Riolo—who carefully kept track of his medical history, diagnosis, treatment and PSA levels—insisted his HMO reimburse him the cost for his first year’s “alternative” treatment and the organization granted him that request, giving him a one-time-only payment of $30,000.

Riolo took his last Lupron shot in June 1998. By August of that year, following the treatment plan of Brodie and the hospital in Mexico, Riolo’s PSA level dropped down to 1.0. But that wasn’t all. For the past two years, using only alternative treatments and natural medicines, Riolo’s PSA reading seems to have stabilized at a striking 00.1. His conventional doctors don’t quite know how to explain this. They had given a death sentence to a man who now seemed free of cancer.

“If you tell most people about Dr. Brodie and how he helped you with your cancer they think you’re nuts,” says Riolo. “They call him a quack and they call him an outcast … but he’s what’s giving people hope.”

Today Riolo appears vigorous and healthy for his age. He goes to the gym three times a week and works full time with his wife and son at his Bronco Parts business near Watt Avenue. He feels “real good” these days. Better, in some ways, than he did before the cancer diagnosis.

“I learned how it works,” he says. “I’ll go to a regular doctor’s hospital if I’m in an auto accident or something like that, or for a tetanus shot. But I’ll never go there for cancer.

“They can’t drag me there for cancer.”

Margarita Amico checked into a Sacramento hospital one morning last April for a surgical biopsy of a painful lump in her left breast. She was assured by medical staff that cancerous lumps don’t cause pain so she wasn’t too worried. Still, the former geriatrics nurse told the doctor “if you find cancer, go ahead and do the whole thing.” When she woke up four and a half hours later, everything had changed.

“I knew my breast was gone,” she says. “I knew I had cancer.”

Sitting in a Reno medical office 12 months later, in the calming “infusion room” at Brodie’s office, Amico talks about the journey she has been on since the day she was diagnosed with an aggressive form of breast cancer. Advised by her doctor at that time to go forward with a standard follow-up of chemotherapy and radiation, she and her close family decided instead to opt for a more holistic healing plan. They sought alternative practitioners and found Brodie in Reno. Amico, 61, adopted Brodie’s therapies, taking the infusions, adhering to the recommended diet.

Four months later, the cancer returned. This time, she decided to proceed with both chemotherapy and a six-week course of daily radiation treatment, a program that is still underway. Since her original diagnosis and surgery, she switched Sacramento doctors and is now undergoing her conventional care at the UCD Medical Center. Amico has nothing but praise for the treatment she has received from the doctors and staff at UCDMC. Still, she fully believes that her decision to undergo non-conventional treatment from Brodie has made her healthier, stronger, better able to deal with the toxic effects of her conventional treatment. “Because of Dr. Brodie, it has not been the terrible experience like you hear about,” she says. “I got nothing extreme. These treatments help, they really helped.”

“Basically, we believe in the body’s ability to fight cancer,” says Brodie. “We do not seek to replace or eliminate traditional methods … our methods can and should be complementary to them.” Once patients like Amico go home from Brodie’s, they are put on a healthful diet and on a home-care plan, as Riolo was, of specific vitamins and supplements. “We have do’s and don’ts,” says Brodie. “We spend quite a bit of time talking to them about their habits and about things [like stress] we think they should change about their lifestyle.”

Amico appreciates that Brodie presents himself as a partner on her medical journey, not an all-knowing dictator. “Dr. Brodie never told me not to take a certain treatment,” she says. “Never. He doesn’t tell you do this, don’t do that. He’s willing to try whatever will work.”

Amico, who has paid thousands of dollars out of pocket for alternative treatments that are uniformly not covered by health insurance, hopes the day is not too long off when patients in California, as well as the rest of the country, can have freedom of choice to determine what type of cancer therapy they want. “It’s just stupid,” she says about the fact that alternative cancer care is legal in Nevada but not in California. “It’s not common sense.”

There is one paradigm that teaches that disease is external to the body; that one must isolate and destroy it. But there is another view that instructs that wellness is created by an interaction of internal and external environments. In this paradigm, the mind and body are integrated. Cancer is seen as a systemic disease, not a localized tumor that just happens to appear in a particular part of the body.

Brodie—and a handful of physicians who have also set up alternative practices in Nevada because California won’t have them—clearly embraces the latter paradigm. His logic goes like this: if there are many interacting factors that contribute to the formation of cancer, so must there be “multiple treatments that can contribute to its demise.”

“I would say alternative medicine is growing in acceptance,” says Brodie. Indeed, some studies indicate that half of all Americans diagnosed with cancer each year now seek complementary care. It’s important to note, in this context, that many cancer patients seek such care for sheer quality of life purposes, i.e. after a terminal diagnosis they choose to live out the rest of their lives without undergoing the toxic effects of chemotherapy or radiation. When asked how many cancer patients die after an alternative course of treatment, Brodie responds that of course, and as with conventional medicine, many diagnosed with terminal cancer do die. He reiterates that most of his practice is complementary to conventional treatment but adds this: “I can say that at least 80 percent of the patients have better outcomes and a reduction of undesirable side effects.”

Dr. James Forsythe, a Reno oncologist who also provides complementary cancer care from Nevada, agrees that awareness of alternatives has risen. But the traditional remains the path of least resistance, he says. “I go to conferences and I don’t hear a word about using anything but pharmaceutical drugs for cancer,” he said. “They believe alternative therapies have no basis in fact—no thousand-patient, double-blind control studies.” In fact, Forsythe believes most alternative approaches will never have the “basis in fact” that conventional medicine requires. “You’re not just doing one thing with a patient,” he said. “You’re doing a combination of things. So it’s very hard statistically to evaluate what’s having impact.”

Meanwhile, conventional physicians like Scudder continue to prescribe only cancer treatments that have been found to be “safe and effective” after testing that follows a strict set of scientific guidelines. “We really are working on these things,” says Scudder, pointing to the many studies now underway, for example, on the subject of how nutrition may impact cancer. “But it will probably be our children or grandchildren who will benefit from the research that’s going on now.”

Today in California, state law still forbids doctors from prescribing alternative cancer treatments. Unlike Nevada, Oregon and Arizona, the state of California still refuses even to license naturopathic physicians so as to enable them to write prescriptions and order diagnostic tests. Indeed, says health advocate Frank Cuny, it is well-recognized that California remains the most restrictive state in the nation when it comes to alternative medicine. Perhaps this is because the lobbying arm of the HMOs—which ultimately represent the interests of conventional medicine—recognizes California as a powerful economic force and bell-wether state, he says. Last year, for this reason, Cuny and his Oroville-based group supported SB 2100, the “Physicians Right To Practice,” authored by Senator John Vasconcellos. To pass, the bill was turned into a modified “study” bill. As a result, a committee of the state Medical Board will soon complete its recommendations on how, in the legislation’s wording, to “establish policies related to the practice of alternative medicine in California,” including in relation to cancer. The board will report the committee’s findings to the Legislature later in May.

“The bottom line,” says Brodie, “is that government has no right at any level to interfere with the doctor-patient relationship. This holds especially true when the patient is suffering from a fatal illness.”

Today, when Pete Riolo opens the cabinet above his kitchen counter, instead of condiments and canned goods, there reside dozens of accumulated containers full of vitamins, supplements and other barely pronounceable natural products. The cupboard looks like the homeopathic section at the local natural foods co-op.

The fact that the ex-cop has been cancer-free for two years now seems presumably to do with these products, a three-week stay at a hospital in Mexico and Brodie’s “forbidden” medical treatments. Ultimately, Riolo’s tale of survival is one anecdotal story in a sea of others that might be told, from conventional and non-conventional perspectives, about those who have experienced this deadly disease. Still, the ex-cop is now a true believer in alternative medicine and wants desperately to get the word out to men suffering from prostate cancer. He hopes to someday write a book detailing his cancer recovery.

“People don’t know they don’t have to die,” he says.

Meanwhile, Margarita Amico pins her hopes on the dual approach and prays for a future when patients like her can benefit from the best medicine there is to offer without it being judged more or less worthy for being “conventional” or “non-conventional.”

Now midway through her radiation treatments at UCD Medical Center, still convinced of the value of her ongoing alternative therapy with Dr. Douglas Brodie, the cancer patient takes a deep breath when asked if she has learned any life lessons from her journey with cancer. Slowly, Margarita Amico says this: “Tell them it’s about learning to be comfortable with who you are,” she says. “Tell them it’s about being connected in your mind and body and spirit. And tell them we should get to choose.”